South African Isotope Facility
SAIF Expands South Africa's Capacity for Life-Saving Radioisotopes
Boosting South Africa's healthcare capacity by increasing radioisotope production for thousands of cancer patients.
The South African Isotope Facility (SAIF) marks a groundbreaking advancement in cancer treatment and nuclear medicine research, positioning South Africa as a leader in the production of high-energy radioisotopes. Housed at iThemba LABS, SAIF is equipped with a dedicated cyclotron capable of producing advanced therapeutic radioisotopes, such as alpha-particle emitters like 211Astatine and 225Actinium, which target and destroy cancer cells with unprecedented precision. This expanded capacity is expected to significantly increase the availability of life-saving isotopes for both local and international use, while also freeing up critical infrastructure for full-time research. SAIF is not only addressing the continent's growing cancer burden but also fostering future innovation by training the next generation of scientists, engineers, and healthcare professionals, driving forward the application of cutting-edge science and technology to improve public health.


Local Employment and Economic Impact
The SAIF project created over 150 man-years of labor and will continue to generate jobs, with 53 new permanent positions for the operation and maintenance of the new cyclotron and isotope production facilities.

Improved Healthcare Outcomes
By increasing the availability of life-saving isotopes, SAIF is expected to multiply the number of patients benefiting from treatments by five to seven times, enhancing healthcare for up to 35,000 patients annually.

Skills Development and Training
SAIF provides a platform for training future generations of scientists, engineers, and technicians in accelerator technology, nuclear physics, and isotope production, with more than 21 students expected to benefit annually.
The SAIF Journey
Below is a timeline of key milestones, from the project's inception to its future projections, outlining its journey toward transforming cancer treatment and scientific advancement in South Africa.
2017
SAIF project initiated with a strategic long-range plan to expand isotope production and research capabilities at iThemba LABS.
2019
First funding for the SAIF project approved, marking a significant step toward realizing the expansion of research and radioisotope production capacity.
2020
Supply contract for the new dedicated cyclotron signed, laying the foundation for new infrastructure development.
2021
Construction of new infrastructure commenced to accommodate the advanced cyclotron and associated facilities for isotope production.
2023
March 1st the first beam produced by the new cyclotron, 43 months after the supply contract was signed, demonstrating the success of the facility's expansion.
June 09 SAIF inauguration, marking a milestone in expanding South Africa's radioisotope production and research capabilities.
2024
First delivery to client.
-->
2030
SAIF’s increased production capacity is expected to benefit up to 35,000 patients annually, with the potential to play a critical role in addressing Africa’s growing cancer burden as cancer becomes the leading cause of death on the continent, according to WHO projections.

Old Faure Rd, Eerste River, Cape Town, 7100